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motor root lesions may weaken the quadriceps, thigh adductor, and iliopsoas; L4 root lesions weaken the anterior tibial innervated muscles L1 root pain is projected to the groin and L2 to the lateral hip Motion of the spine and 4th Lumbar Vertebra certain positions are most evocative of root pain; if the pain is constant in all positions, root irritation is seldom the cause L4 Root Much has been made of a distinctive syndrome associated with extreme lateral disc protrusions, particularly those situated within the proximal portion of the interver5th Lumbar Protruded tebral spinal foramina Unremitting radicular pain without Vertebra Discs back pain and a tendency to worsen with extension of the back and torsion toward the side of the herniation are said to be characteristic Also, in rare instances of lumbar inL5 Root tradural disc rupture, there may not be sciatic pain because the free fragment does not impinge on the roots of the cauda equina Both of these con gurations may confound clinical and radiologic diagnosis and make surgery more dif cult S1 Root Rarer still are protrusions of thoracic intervertebral discs (05 percent of all surgically veri ed disc protrusions, according to Love and Schorn) The four lowermost thoracic interspaces are the most frequently involved S2 Root Trauma, particularly hard falls on the heels or buttocks, is an important causative factor Deep boring spine pain; root pain circling the body or projected to the abdomen or thorax (sometimes simulating visceral disease); paresthesias Figure 11-4 Mechanisms of compression of the fth lumbar and rst sacral roots A below the level of the lesion; loss of sensation; both deep lateral disc protrusion at the L4-L5 level usually involves the fth lumbar root and and super cial; and paraparesis or paraplegia are the usual spares the fourth; a protrusion at L5-S1 involves the rst sacral root and spares the fth lumbar root Note that a more medially placed disc protrusion at the L4-L5 level (crossclinical manifestations A herniated lumbar disc at one interspace may com- hatched) may involve the fth lumbar root as well as the rst (or second and third) sacral root press more than one root (Fig 11-4), and it follows that the symptoms will then re ect this involvement Furtherbecomes inevident on CT As indicated earlier, we turn to CTmore, the above descriptions of single root compression refer myelography for a re ned de nition of the root sleeves and may mainly to signs and symptoms of atypical posterolateral disc prouse the EMG to corroborate subtle ndings Usually MRI will demtrusion Very large central disc protrusions may compress the enonstrate the extruded disc at the suspected site and will also exclude tire cauda equina with a dramatic syndrome that includes intense herniations at other sites or an unsuspected tumor (Fig 11-5) At low back and bilateral sciatic pain, incomplete paraparesis, loss of the lumbosacral junction there is a wide gap between the posterior both ankle jerks, and most characteristic, varying degrees of urinary margins of the vertebrae and the dural sac, so that a lateral or central retention and incontinence This demands immediate surgical atprotrusion of the L5-S1 disc may fail to distort the dural margin as tention seen on myelography Anomalies of the lumbosacral roots may lead to errors in loWe nd, as do Leyshon and coworkers, that the needle EMG calization (see descriptions by Postaccini et al) The combined rupstudy is abnormal, showing brillation potentials in denervated ture of two or more discs occurs occasionally and further complimuscles after 1 or 2 weeks in over 90 percent of cases Loss or cates the clinical picture When both the L5 and S1 roots are marked asymmetry of the H re ex is another useful indication of compressed by a large herniated disc, the signs of the S1 lesion S1 radiculopathy and corroborates the loss of an Achilles re ex usually predominate The nding of denervation potentials in the paraspinal muscles Herniation may occur into the adjacent vertebral body, giving (indicating root rather than peripheral nerve lesions) and in muscles rise to a so-called Schmorl nodule In such cases there are no signs that conform to a root distribution is also helpful provided that at of nerve root involvement, although back pain may be present, least 2 or 3 weeks have elapsed from the onset of root pain But sometimes recurrent and referred to the thigh Most often, these we would emphasize that, while useful information is sometimes circular densities adjacent to the endplate of the vertebral body are to be gained from EMG, it is needed in only a fraction of cases found incidentally on CT or MRI and often provides only corroborating data Diagnosis When all components of the syndrome are present, It is most important to keep in mind that a number of disc diagnosis is easy; but most neurologists prefer to corroborate their abnormalities, frequently observed on MRI and loosely referred to clinical impression by MRI of the spine from L3 to S1 or, with as herniation, may be incidental ndings, unrelated to the paless ef cacy, by CT MRI is favored because of the advantages of tient s symptoms Jensen and colleagues, in an MRI study of the the sagittal image and the clarity of the anatomic relationships belumbar spine in 98 asymptomatic adults, found that in more than tween discs and nerve roots; however, the differences are modest half there was a symmetrical extension of a disc (or discs) beyond except when the extruded fragment is molded into the adjacent the margins of the interspace (bulging) In 27 percent, there was a bone (as it is prone to be with laterally extruded fragments) and.

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Whenever you are unsure of the proper disposal procedures for a component, look for its material safety data sheet (MSDS) An MSDS is a standardized document that contains general information, ingredients, and fire and explosion warnings as well as health, disposal, and safe transportation information about a particular product Any manufacturer that sells a potentially hazardous product is required to issue an MSDS for it If an MSDS didn t come with a particular component, contact the manufacturer or search for it on the Internet A number of websites, including sites sponsored by

Figure 11-5 Lumbar disc herniation on T1-weighted MRI A Sagittal view of large L5-S1 herniated nucleus pulposus (arrow) The extruded material has the same signal characteristics as the normal adjacent disc B Axial view of same disc (arrow) showing the paracentral mass that obliterates the epidural fat signal and compresses the S1 nerve root

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focal or asymmetrical extension of the disc beyond the interspace (protrusion), and in only 1 percent was there more extreme extension of the disc (extrusion) These ndings emphasize the importance of using precise terms in describing the MRI abnormalities and always evaluating these abnormalities in the light of the patient s symptoms Management of Ruptured Lumbar Disc In the treatment of an acute or chronic rupture of a lumbar disc, complete bed rest is usually advised and appears to be helpful, although even this time-honored tenet has been questioned by the results of several randomized studies (Vroomen et al) Nonetheless, we still adhere to this form of treatment, and it is associated with marked improvement in the majority of patients Analgesic medications, either NSAIDs or narcotics, may be required for a few days In a few but not all patients with severe sciatica, we have been impressed with the temporary relief afforded by administration of oral dexamethasone for several days, 4 mg every 8 h, although this has not been studied systematically The only indication for emergency surgery is an acute compression of the cauda equina by massive disc extrusion, causing bilateral sensorimotor loss and sphincteric paralysis or severe unilateral motor loss Although not necessarily the recommended course, it should be pointed out that there are instances where even a dramatic syndrome of cauda equina compression has cleared up after several weeks of bed rest Traction is of little value in lumbar disc disease, and it is best to permit the patient to nd the most comfortable position After a brief period at rest, the patient can be allowed to resume activities gradually, sometimes with the protection of a brace or light spinal support The patient may suffer minor recurrence of the pain but should be able to continue his or her usual activities, and most will eventually recover The more routine measures for man-.

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aging back pain, as mentioned in an earlier section, may also be helpful If the pain and neurologic ndings do not subside in response to this type of conservative management or the patient suffers frequent disabling acute episodes, surgical treatment must be considered Most of the patients requiring surgery because of intractable pain within days after a brief trial of bed rest will be found to have a large extruded disc fragment This should be preceded by MRI to localize the lesion (and exclude intra- or extradural tumors); if no lesion is found, CT myelography and EMG may be helpful in detecting lateral recess stenosis and other causes of sciatica (see further on) The surgical procedure most often indicated for lumbar disc disease is a hemilaminectomy, with excision of the disc fragment In cases with sciatic pain due to L4-L5 or L5-S1 disc ruptures, 85 to 90 percent are relieved by operation Rerupture occurs in approximately 5 percent (Shannon and Paul) Arthrodesis (spinal fusion) of the involved segments is indicated only in cases in which there is extraordinary instability, usually related to extensive surgery or to an anatomic abnormality (such as spondylolysis) In our experience and that of our colleagues, the features that are predictive of better outcome from decompressive surgery are younger age, a clear precipitating event for the back and sciatic pain, clinical features that are restricted to compression of a single nerve root, and the absence of chronic or frequently recurrent back pain Issues regarding the use of microscopic surgery and various special techniques are best left to surgical colleagues, but the results are comparable for most techniques The treatment of nerve root compression with repeated epidural injections of methylprednisolone enjoyed a period of popularity, but controlled studies of this procedure have failed to con rm its sustained ef cacy (White et al; Cuckler et al), and the procedure is not without complications Carette et al have found.

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